Our paper, revealing long non-coding RNA MaIL1 as a component of the TLR4-TRIF immune signaling pathway is now out in PNAS. We reveal MaIL1 as a critical component of type I interferon-mediated innate antibacterial defense in human macrophages. The paper also reports previously unknown subclasses of long non-coding RNAs (lncRNAs), co-sedimenting with different cellular protein machineries, and describes a new workflow for lncRNA mechanistic investigation.
We are now member of the "Sonderforschungsbereich" SFB-TR84 - Innate Immunity of the Lung (https://www.sfb-tr84.de/). Our project will further elucidate the mechanistic implications of lncRNAs in the human mononuclear phagocyte system with an emphasis on innate defense against bacterial agents of pneumonia.
Welcome to rna-lab.org, the new website of the Schulte lab (Institute for Lung Research, Philipps-University Marburg). This site is still under construction and will be populated with more content soon. Meanwhile also visit the website of the Institute for Lung Research.